Sufficient Indigo Carmine (indigotindisulfonate) is contained in each 5 mL ampule to permit accurate withdrawal and … A member of the class of indolones obtained by formal 2,2'-oxidative coupling of two molecules of 3-oxo-2,3-dihydroindole-5-sulfonic acids. 1. DESCRIPTION. Practically insol in most other organic solvents. It is approved for use as a food colorant in the U.S and E.U., It has the E number E132. As a pH indicator, it is blue at pH 11.4 and yellow at 13.0. C.I. Certolake Tartrazol Yellow. Indigo carmine, or 5,5′-indigodisulfonic acid sodium salt, is an organic salt derived from indigo by sulfonation, which renders the compound soluble in water. Appearance: Indigo carmine; Indigo carmine. In European countries, E-numbers for permitted food colours are from E 100 to E 199, divided into yellows (E 100-109), oranges (E 110-119), reds (E 120-129), blues and violets (E 130-139), greens (E 140-149), browns and blacks (E 150-159), and others (E 160-199). The LibreTexts libraries are Powered by MindTouch® and are supported by the Department of Education Open Textbook Pilot Project, the UC Davis Office of the Provost, the UC Davis Library, the California State University Affordable Learning Solutions Program, and Merlot. It is an indicator at pH 11.5-14, changing from blue to yellow. Indigo Carmine is excreted largely by the kidneys, retaining its blue color during passage through the body. Fig. Indigo carmine is also a redox indicator, turning yellow upon reduction.Another use is as a dissolved ozone indicator through the conversion to isatin-5-sulfonic acid. Tartrazine aluminum lake. The structural formula is: CLINICAL PHARMACOLOGY. 11671 Yellow. It almost always contains sodium chloride or sulfate used for "salting" it out. Watch the recordings here on Youtube! An organic sodium salt resulting from the formal condensation of indigo carmine (acid form) with two equivalents of sodium hydroxide. FD&C Yellow 5 Lake. The biological half-life is 4 to 5 minutes following intravenous injection. (, 2-(1,3-Dihydro-3-oxo-5-sulpho-2H-indol-2-ylidene)-3-oxoindoline-5-sulphonic acid. View information & documentation regarding Indigo carmine, including CAS, MSDS & more. It is also marketed as a paste with water, the dye contents varying according to specification or requirements of the user. This service is an Elixir Core Data Resource. Indigo carmine, or 5,5′-indigodisulfonic acid sodium salt, is an organic salt derived from indigo by sulfonation, which renders the compound soluble in water. 19140 Aluminum Lake. As a viability stain, it will stain dead cells blue while living cells remain unstained. EC 235-428-9 This reaction has been shown not to be specific to ozone, however: it also detects superoxide, an important distinction in cell physiology. Indigo Carmine is excreted largely by the kidneys, retaining its blue color during passage through the body. For more information contact us at email@example.com or check out our status page at https://status.libretexts.org. It is also a pH indicator. (2E)-disodium salt 2-(1,3-dihydro-3-oxo-5-sulfo-2h-indol-2-ylidene)-2,3-dihydro-3-oxo-1h-indole-5-sulfonic acid; disodium (2E)-3-oxo-2-(3-oxo-5-sulfonato-1,3-dihydro-2H-indol-2-ylidene)-2,3-dihydro-1H-indole-5-sulfonate; Disodium (2E)-3-oxo-2-(3-oxo-5-sulfonato-1,3-dihydro-2H-indol-2-ylidene)-5-indolinesulfonate; Disodium (2E)-3-oxo-2-(3-oxo-5-sulfonato-1,3-dihydro-2H-indol-2-ylidene)indoline-5-sulfonate. INDIGO CARMINE (indigotindisulfonate sodium) Injection, USP. 1SD, UK +44 (0)1223 49 44 44, Copyright © EMBL-EBI 2018 | EBI is an outstation of the European Molecular Sigma-Aldrich offers a number of Indigo carmine products. Elimination of the dye begins soon after injection, appearing in the urine within 10 minutes in average cases. Used as a tissue stain, pH indicator and viability stain. It is approved for use as a food colorant in the U.S and E.U. ChEBI Name indigo carmine (acid form) ChEBI ID CHEBI:90117: Definition A member of the class of indolones obtained by formal 2,2'-oxidative coupling of two molecules of 3 … EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 Indigo carmine, or 5,5′-indigodisulfonic acid sodium salt, is an organic salt derived from indigo by sulfonation, which renders the compound soluble in water. A food additive that imparts colour to food. Slightly sol in alcohol. A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.