(2E)-2-(3-Oxo-1,3-dihydro-2H-indol-2-ylidene)-1,2-dihydro-3H-indol-3-one, c1ccc2c(c1)C(=O)/C(=C\3/C(=O)c4ccccc4N3)/N2 Indigo dye is a dark blue crystalline powder that sublimes at 390–392 °C (734–738 °F). Indocyanine Green for injection permits recording of the indicator-dilution curves for both diagnostic and research purposes independently of fluctuations in oxygen saturation. The technique for both methods is as follows. Inject the calculated amount of dye (0.5 mg/kg of body weight) into the lumen of an arm vein as rapidly as possible, without allowing the dye to escape outside the vein. More info about absorbents, including situations to watch out for... National Oceanic and Atmospheric Administration, Indigo carmine; (FD&C blue No 2) (860-22-0), [DELTA2,2'-BIINDOLINE]-5,5'-DISULFONIC ACID, 3,3'-DIOXO-, DISODIUM SALT, 3,3'-DIOXO-(DELTA(SUP 2,2')-BIINDOLINE)-5,5'-DISULFONIC ACID. Deaths from anaphylaxis have been reported following Indocyanine Green for injection administration during cardiac catheterization. Nowadays, cotton cloth works perfectly in this process. indikon, meaning Indian). (2E)-2-(3-Oxo-1,3-d ihydro-2H-indol-2-y lidène)-1,2-dihydro-3H-indol-3-one [French] [ACD/IUPAC Name] [D2,2'-Biindoline]- 3,3'-dione [δ2,2'-Biindoline]- 3,3'-dione It is one of the oldest dyes used for textiles and printing. Indigo carmine, or 5,5′-indigodisulfonic acid sodium salt, is an organic salt derived from indigo by sulfonation, which renders the compound soluble in water. It is strongly recommended that the same dye that was used for the injections be used in the preparation of these standard dilutions. 2005-07-19. In the Levant, the indigo industry survived much beyond the sugar industry. Hemolysis is not expected to interfere with a reading. Considered the king of blues, indigo is extensively used in fabric dyeing for its rich and intense colour. Indigo Carmine. Lower Explosive Limit (LEL): data unavailable, Upper Explosive Limit (UEL): data unavailable, Autoignition Temperature: data unavailable, Vapor Density (Relative to Air): data unavailable. The Middle East imported indigo from India, as it name suggests it (from Gr. mukhayyar)... Indigo cultivation was still a very common production of the Jordan Valley at the 19th century, but started declining, as in general the local agriculture in the whole area, affected by an external bureaucratic oppression, the exploitation of the peasantry and the degeneration of the whole farming system crumbling, following the report of the 19th century travelers, under the inefficiency and the corruption of the governmental Ottoman authority. including trade names and synonyms. The chemical formula of indigo is C16H10N2O2. Because many drugs are excreted in human milk, caution should be exercised when Indocyanine Green for injection is administered to a nursing woman. *Dichromatic earpiece densitometer supplied by The Waters Company, Rochester, Minnesota. below, Indigo Dye Extraction video, ref. Determination Using Disappearance Rate of Dye: To calculate the percentage disappearance rate, obtain samples at 5, 10, 15 and 20 minutes after injecting the dye. Normal Values: Percentage disappearance rate in healthy subjects is 18 to 24% per minute. A recording instrument (oximeter or densitometer) is attached to a needle or catheter for sampling of the dye‑blood mixture from a systemic arterial sampling site. There are no data available describing the signs, symptoms, or laboratory findings accompanying overdosage. These doses of the dye are usually injected in 1 mL volume. This step starts the fermentation of the leaves and the release of the colorless chemical agent, the indican, together with an queasy odor. Available for Android and iOS devices. 6. It is an indicator at pH 11.5-14, changing from blue to yellow. or It is not known whether this drug is excreted in human milk. Rocky Mount, NC 27804 It is approved for use as a food colorant in the U.S and E.U. However, with the technological advances that occurred subsequently to the Islamic expansion in Asia, the cultivation of indigo was imported to the Middle East in order to also produce it locally. Indigo Disulfonate. This unique shade of blue is called indigo, and it comes from an organic dye derived from Indigofera plants. These characteristics make Indocyanine Green for injection a helpful index of hepatic function. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. The 2D chemical structure image of INDIGO is also called skeletal formula, which is the standard notation for organic molecules. Indigo can be produced from different type of plants (about 300 kind of plants contain the indigotin, the basic chemical compound producing the blue color). pH adjusted, when necessary, with Citric Acid and/or Sodium Citrate. Indigo even became the main crop cultivated in the Jordan Valley. (10 mL each), Distributed by: STORAGE: Store at 20° to 25°C (68° to 77°F) Generic Name: indigotindisulfonate sodium Dosage Form: injection, solution Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton. Sterile techniques should be used in handling the dye solution as well as in the performance of the dilution curves. Today the common plant used to produce indigo is the Indigofera tinctoria, also called the true indigo. It is this second option that is implemented in Ghawr Safi, following the traditional method still in use today in India.The indigo craftspeople keep discrete on some details of the process, however, roughly speaking, indigo is extracted by the following steps: - The leaves are soaked and pressed in a water tank. Lake Forest, IL 60045 USA, For Intravenous Administration 25 mg/Vial Kit Rx Only - Sterile. Indocyanine Green for injection USP is a sterile, lyophilized green powder containing 25 mg of Indocyanine Green with no more than 5% sodium iodide. USP vials (25 mg each) In the past, camel urine was also used. (NTP, 1992), Flash point data for this compound is not available, but it is probably combustible. After reconstitution, use within 6 hours. This concentration is then successively halved by diluting 2 mL of the previous concentration with 2 mL of distilled water. indigotin. Infants - 1.25 mg. The extraction of indigo can be done through two different processes: by drying indigo leaves and crushing them into a powder that will be then diluted into water or by soaking directly fresh leaves. The chemical name for Indocyanine Green is 1 H -Benz [ e ]indolium, 2- [7- [1,3-dihydro-1,1-dimethyl-3- (4-sulfobutyl)-2 H -benz [ e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3- (4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Wash all contaminated surfaces with a strong soap and water solution. For Intravenous Administration Indocyanine Green for injection is taken up from the plasma almost exclusively by the hepatic parenchymal cells and is secreted entirely into the bile. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Create. Safety and effectiveness in pediatric patients have been established. Grand Island, NY 14072 USA Indigo, an important and valuable vat dyestuff, obtained until about 1900 entirely from plants of the genera Indigofera and Isatis. The duration of the oxygenation process will determine the quality of the pigment. [See USP Controlled Room Temperature]. Indigo carmine is an organic sodium salt resulting from the formal condensation of indigo carmine (acid form) with two equivalents of sodium hydroxide. Under sterile conditions, the Indocyanine Green for injection powder should be dissolved with the Sterile Water for injection provided for this product, and the solution used within 6 hours after it is prepared. Indigo-dyeing has a long history, and the method is still as popular as it was centuries ago. substance. Color of aqueous solutions fades on standing. Until the emergence of the prosperous centuries of the Islamic Agricultural Revolution, The Middle East imported indigo from India, as it name suggests it (from Gr. intravenously unless rendered nearly isotonic.